Puss stumbles upon the legendary hidden city of San Lorenzo, and soon finds himself forced to protect it from thieves.
Puss is tricked into going on a quest with an old friend, Jack Sprat. What starts out as a mission to save a princess soon turns dangerous.
The Golem, a giant clay enemy Puss has been outrunning for years, comes to San Lorenzo. With the help of Artephius, Puss may finally defeat his foe.